Scientist - Target Identification/validation Expert - Berlin, Deutschland - Bayer

Bayer

Geprüftes Unternehmen

Berlin, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

At Bayer we're visionaries, driven to solve the world's toughest challenges and striving for a world where ,Health for all, Hunger for none' is no longer a dream, but a real possibility. We're doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining 'impossible'. There are so many reasons to join us. If you're hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there's only one choice.

Scientist - Target Identification/Validation Expert Research Immuno-Oncology (M/F/d)

The Scientist - Target Identification/Validation Expert Research Immuno-Oncology (M/F/d) develops and utilizes strategies for the identification of potential new drug target molecules to initiate projects for novel cancer therapeutics development with a focus on Immuno-Oncological approaches.

As a pre-D1 expert, at least junior scientist, duties include design and execute immunological and cancer-related pre-clinical in vitro/ex vivo/ in vivo models for validating novel biology and pathways.

YOUR TASKS AND RESPONSIBILITIES

Lead target identification initiatives and provide biological guidance and deep diseaseunderstanding with expertise in cancer and Immunology for data mining approaches utilizing scientific creativity, independent and outofthebox thinking
Utilize stateof the art data sources for target/ pathway identification as Real-Word data, literature databases and gene expression data (RNA seq, Single Cell seq, Exon seq, CITE seq, spatial transcriptomics) with the help of Bayer's bioinformatics department
Design and execute preclinical strategies to validate the biology of novel drug targets as starting points for new drug discovery programs, as well as to serve as project lead for preclinical target validation projects
Independently establish and conduct immune cells assays, and cancerrelated models in vitro/ex vivo/in vivo to validate novel target / pathways for relevance in the human disease
Follow continuously scientific developments in the field, interpret and effectively communicate scientific findings and project ́s progress in department and community meetings
Work and collaborate in a team with biologists, bioinformaticians and (bio)chemists across Bayer ́s pharmaceutical division as well as with external CRO and academic partners, with a specific focus on collaboration with Joint Immunotherapy Laboratory at the DKFZ (Heidelberg)
Work with geneticallymodified, radioactively labelled and infectious material, as well as animal experiments and comply to legal requirements and regulations (as applicable: Gentechnik, Biostoffverordnung, Infektionsschutzgesetz, Tierversuchserlaubnis)

WHO YOU ARE

PhD in Immunology or Biology or in related fields, MD-PhD in Immunology is a plus
Expert knowledge in Cancer Biology, Immuno-Oncology and Immunology
Prior working experience in a PostDoc position in the field of Immunology or Immuno-Oncology as well as first experiences in a pharmaceutical company or biotech in the field of Immuno-Oncology
Expertise, practical knowledge and track record (scientific publication) of bioinformatic data mining approaches for biology and disease understanding
Capability to generate scientific and therapeutic hypotheses and experimentally validate or devalidate them utilizing immunology / diseaserelated assays
Experience in a variety of techniques of cellular and molecular biology, flow cytometry and experience with in human multicellular in vitro / ex vivo and mouse in vivo models
Creative and flexible thinking, with excellent organizational skills including a sense of responsibility and urgency and ability to adapt to a dynamic research environment and the ability to work in teams as well as independently
Excellent verbal and written communication and presentation skills in English

YOUR APPLICATION

This is your opportunity to tackle the world's biggest challenges with us: Maintaining our health, feeding growing populations and slowing the rate of climate change.

You have a voice, ideas and perspectives and we want to hear them. Because our success begins with you. Be part of something big. Be Bayer.

Location:
Berlin

Division:
Pharmaceuticals

Reference Code:780499