Research Associate - Dresden, Deutschland - Technische Universität Dresden

Technische Universität Dresden

Geprüftes Unternehmen

Dresden, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

CUBE and the Center for Regenerative Therapies (CRTD), are equipped with state-of-the-art facilities
- technologie/technologieplattform). They are part of a rich and collaborative environment that
includes the Faculty of Mathematics and Natural Sciences, the Faculty of Medicine, the Max-Planck

Institute of Molecular Cell Biology and Genetics (MPI-CBG), and the Leibniz Institute for Polymer

Research (IPF). For TUD diversity is an essential feature and a quality criterion of an excellent
university. Accordingly, we welcome all applicants who would like to commit themselves, their
achievements and productivity to the success of the whole institution. For TUD diversity is an essential
feature and a quality criterion of an excellent university. Accordingly, we welcome all applicants who
would like to commit themselves, their achievements and productivity to the success of the whole
institution.

At the
Biotechnology Center (BIOTEC), an Institute of the
Center for Molecular and Cellular

Bioengineering (CMCB), the
Research Group Biomedical Genomics (Dr. Anna Poetsch) offers a

position as**
Research Associate / Postdoc Computational Genome Biology (M/F/x)***starting on
June 1, 2023._ _The position is limited until March 31, 2025.

An extension to approximately
4 years is anticipated. The period of employment is governed by the Fixed Term Research Contracts
Act (Wissenschaftszeitvertragsgesetz-WissZeitVG)._ _The position offers the chance to obtain further
academic qualification.

Tasks: 3D genome architecture plays a major role in genome organisation, gene regulation and
genome stability. Thus, deregulation of 3D genome architecture is also an important mechanism
contributing to disease.

To strengthen our diverse team, we are looking for a postdoctoral fellow to study genome architecture
as part of the DFG priority program "Spatial Genome Architecture in Development and Disease
(Genome3)". We will particularly focus on the nuclear pore and how it affects gene regulation and
genome stability in neural development and brain cancer. The project is a collaboration between the
lab of Tomohisa Toda on "Nuclear architecture in neural plasticity and ageing" and the computational
Research Group of Anna Poetsch on "Biomedical Genomics" at the Biotechnology Center of the TU
Dresden, where this position will be based.

The position will offer an exciting collaborative interdisciplinary research project embedded in a
analysis to investigate how 3D genome architecture in the nuclear pore affects gene regulation and
genome stability with data on genome architecture (e.g. HiC, Hi-ChiP, DamID-HiChiP, MicroC), gene
regulation (e.g. ChiP, DamID-ChiP, ATAC-Seq, RNA-seq), DNA damage (AP-Seq, 8-oxoG, END-Seq),
germline mutations in neurodevelopmental disorders, and somatic mutations in paediatric brain
deep learning methods on genomics data.

Requirements:

- excellent university and PhD degree with experience in molecular biology, computational

biology, genetics, genomics, or equivalent scientific background with an excellent
understanding of genome biology

Comprehensive programming experience in python and/or R.
Demonstrable experience in multiomics data analysis.
Very good interpersonal and communication skills; in particular, the ability to effectively work

- in a diverse, collaborative and interdisciplinary research environment.

Fluency in English written and oral. (German is not required).

The BIOTEC/CMCB is a renowned interdisciplinary and international research institute of the TU
Dresden that boasts a collaborative spirit and cutting-edge technology platforms, including one of the
national genome centres and cutting-edge High Performance Computing resources. The city of
Dresden and the DFG focus program (Genome3) provide numerous opportunities for scientific
exchange and collaboration.

TUD strives to employ more women in academia and research. We therefore expressly encourage
women to apply. The University is a certified family-friendly university and offers a Dual Career
equally qualified, those with disabilities or with equivalent status pursuant to the German Social Code
IX (SGB IX) will receive priority for employment.

motivation, your CV including a list of publications, transcripts of records, and contact details for 2-3
academic references, by
March 15, 2023 stamped arrival date of the university central mail service

BIOTEC, Forschungsgruppe Biomedizinische Genomik, Frau Dr. Anna Poetsch, Helmholtzstr. 10,
Expenses incurred in attending interviews cannot be reimbursed.

Reference to data protection:
Your data protection rights, the purpose for which your data will be processed,