Phd (D/f/m) Institute of Allergology Dm.205b.23 - Berlin-Steglitz, Deutschland - Charité

Charité

Geprüftes Unternehmen

Berlin-Steglitz, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

Arbeitszeit

Teilzeit
Eintrittsdatum

zum nächstmöglichen Zeitpunkt
Dauer der Anstellung

Befristet
Bewerbungsfrist

Einsatzort Charité

Campus Benjamin Franklin, Steglitz
Kennziffer

2383
Entgeltgruppe

E13

Working at the Charité
Charité - Universitätsmedizin Berlin is a joint institution of Freie Universität Berlin and Humboldt-Universität zu Berlin.

Charité was once again voted Germany's best hospital because our employees do an outstanding job every day - in patient care as well as in research, teaching and administration.

Patients from all over the world rely on the expertise of our staff as well as on state-of-the-art diagnostics and treatment methods.

Job Overview

Your responsibilities will include the establishment and validation of these methods and their use to characterize patients with CSU. In addition to samples collected from patients during consultations, sera from a comprehensive and already existing biobank can be used. Furthermore, relevant IgE and IgG autoantibodies from patient sera will be purified by chromatographic methods and investigated with respect to posttranslational modifications such as glycosylation
Project description: Chronic spontaneous urticaria (CSU) is a common autoimmune disease, but its pathomechanisms remain to be elucidated in detail. The two known autoimmune subtypes of CSU, type I and type IIb, remain poorly characterized and currently cannot be diagnosed in routine clinical practice. Therefore, it is unclear how many CSU patients have autoimmune type I or type IIb and how they differ in their immunologic and clinical profiles, including disease activity, duration, and response to treatment.
The aim of this project is to characterize type I and type IIb autoimmune CSU in detail, to determine their prevalence and to identify associated immunological and clinical features. For this purpose, our group is currently developing appropriate methods such as ELISA assays for IgE against autoantigens, peptide arrays for relevant IgE autoantibodies, auto IgE assays as well as in vitro and ex vivo mast cell models.

We are looking for

Experience in handling and researching primary immune cells, possibly also mast cells
Experience in cell biology and molecular biology and biochemical methods (ELISA, Western blot, cloning, CRISPR/Cas, flow cytometry, chromatography)
Experience with in vitro cell culture models
Excellent English skills (oral and written)
High motivation, flexibility, very good organizational skills, ability to work in a team
Enthusiasm for immunology and translational/basic research
Research assistants are given sufficient time for their own scientific work in accordance with their employment contract
We offer close supervision during the training period and beyond as well as flexible working hours

Advantages at the Charité

A relaxed but highly professional collaboration in a familiar, motivated, interdisciplinary team
A futureoriented, varied and challenging job with a high degree of personal responsibility and personal freedom of action
Multicultural team events, wellstructured onboarding with nice colleagues
Extensive free continuing education and training opportunities up to and including university studies
Discounts on many employee offers for shopping, travel, sports
Our company pension scheme provides our employees with additional security in old ageCharité
Universitätsmedizin Berlin is certified for a familyfriendly balance between private life, family and work or studies you can find further information

here

Job Information

Pay scale XXX according to TVöD
VKA
K. The grouping takes place under consideration of the qualification, the respective experience level is calculated from the completed professional years. The annual salary (gross) is given for a fulltime position without annual bonus, allowances and additional services. You can find the collective agreement here.
The working time is parttime with 25,35 hours per week
At our company 30 days of vacation are standard
Reference number: 2383

Ihre Bewerbung:

Ms. Wenke Neumann

phone:

Vorteile und Leistungen:

Faire Löhne und Arbeitskonditionen:

An der Charité erwarten dich Tarifverträge mit fairem Gehalt, vielfältigen Zusatzleistungen und 30 Tagen Urlaub

Interdisziplinäres Arbeiten:

Wir kooperieren mit anderen Kliniken weltweit und arbeiten auch im Alltag interdisziplinär zusammen. Unsere Arbeit ist geprägt von einem kontinuierlichen Austausch untereinander.

Stimulierendes Arbeitsumfeld: