Research Associate - Planegg, Deutschland - iOmx Therapeutics AG

iOmx Therapeutics AG

Geprüftes Unternehmen

Planegg, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Your Tasks and Responsibilities:

You will strengthen our preclinical pharmacology & biomarker development team by contributing to the

- (pre-)clinical research and development of novel immune-checkpoint inhibitors and their further clinical development

Your tasks include:

Design and implementation of cellbased assays to analyze the pharmacological impact of novel immunecheckpoint inhibitors on primary immune cells and tumor cells using various immunological and cellbased assays
Detailed analysis of primary immune cell (lymphoid and myeloid) subsets, their activation and function using flow cytometry and other advanced immunological assays
Design, implementation and qualification of _in vitro_ and _ex vivo_ cellbased and cellfree biomarker assays
Perform routine culture and expansion of primary immune cells, tumorinfiltrating lymphocytes and tumor cell cultures
Careful documentation as well as presentation of your results in internal meetings

What we are looking for:

You hold a degree in biology, biotechnology or related fields, or have completed vocational training as a laboratory assistant such as BTA, MTA, CTA or equivalent with 2+ years of industry experience
Deep knowledge of tumor biology and immunology is advantageous
You have handson experience in immune cell (lymphoid and myeloid) functional assays (cytotoxicity assays, cytokine analysis, polarization assays, mixed lymphoid reaction assays, etc.)
You are experienced in cell biology (isolation and cultivation of primary cells and cell lines, proliferation assays) and immunological techniques, e.g., ELISA, beadbased multiplex assays, multicolor flow cytometry (> 8 colors) including independent panel design, western blot, etc.
Molecular biology assays, such as DNA transfections and transduction are familiar to you
You are proficient with MS Office, GraphPad Prism and FlowJo
Experience in scientific data analysis and visualization, e.g., tSNE, PCA, heatmaps, would be a plus
You are fluent in English (spoken and written)
You are a highly motivated, flexible, and creative individual with excellent communication and interpersonal skills
You are efficient at working in collaborative and diverse teams

Why to join iOmx?:

We are a young biotechnology company with about 50 employees in Martinsried/Munich. We are working in flat hierarchies with short decisionmaking processes and offer a rewarding career in a welcoming, trusting and international work environment.
By joining us you can expect the following:
Opportunity for personal development
Growthoriented and innovationdriven company culture
30 days paid vacation
Flexible working time and much more

About us:

- i_

Omx Therapeutics is a clinicalstage company in the field of immunooncology located in Martinsried/Munich, Germany._
We are focusing on the development of firstinclass cancer immunotherapies, addressing novel immune evasion biologies, which are hijacked by tumors and their microenvironment._
We are looking for highly motivated, selfdriven and competent colleagues who share our vision and wish to contribute to translating this vision into reality._