Phd Position - Bochum, Deutschland - Universität zu Köln

Universität zu Köln

Geprüftes Unternehmen

Bochum, Deutschland

vor 11 Stunden

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

The Uhlirova Lab investigates the pleiotropic functions of the stress-inducible
signaling pathways and downstream mechanisms orchestrating gene expres
- sion in the context of epithelial tissues and innate immune cells. We study how
diverse stress signals modulate transcription factor and spliceosome activities
during development and physiology and how malfunction of transcription
and splicing machinery affects epithelial and immune cell behaviors and the
interactions between the two systems during aging and disease. We combine
functional genetics in Drosophila and mouse models with molecular and cell
biology techniques, biochemistry, omic approaches, and advanced micros
- copy. For more information please visit the Uhlirova Lab website

YOUR TASKS

To study the mechanisms governing the development and functions of

the cellular branch of the innate immune system in health and disease.

To elucidate the mechanisms underlying immune celltissue

interactions in homeostasis and disease states.

To study the crosstalk between transcription and splicing during

innate immune system development and activation.

To investigate how spliceosome malfunction impacts hematopoiesis and

innate immune cell responses during infection and inflammatory diseases.

YOUR PROFILE

Master of Science or equivalent in Biology, Biochemistry, or Biophysics
Motivation, curiosity and creativity, and a strong ability for

problem-solving through critical analytical thinking

Keen interest in the mechanisms of signaling and regulation

of gene expression in development and disease

Ability to drive the project with a high degree of independence
Good communication skills, fluency in English, sense for

teamwork and commitment to high-quality research

Strong background in genetics and molecular biology is essential
Experience with model organisms (e.g. Drosophila, mouse), imaging

techniques, and knowledge of basic bioinformatics tools are welcome

WE OFFER

Interactive and international research group with access to the stateof

- the-art imaging, proteomic, lipidomic and genomic research facilities

A diverse working environment with equal opportunities
Support in balancing work and family life
Flexible working time models
Extensive advanced training opportunities
Occupational health management offers

The University of Cologne is committed to equal opportunities and
considered preferentially in accordance with the Gender Equality Act
of the State of North Rhine-Westphalia (Landesgleichstellungsgesetz
disabilities / special needs or of equal status.

The position is available as soon as possible on a part-time basis (65%). It
is limited to three years. If the applicant meets the relevant wage requi
- rements and personal qualifications, the salary is based on remuneration
group 13 TV-L on the pay scale for the German public sector.

HOW TO APPLY
- a Cover Letter describing your motivation to join our research group
- your academic Curriculum Vitae, including your publication list
- a statement on your scientific achievements, summary (1/2

page) of your Master Thesis project or equivalent
- contact information for two references
- copies of your degree certificates without a photo

The reference number is
Please direct any inquiries and questions to

PhD Position (f/m/x) Immune cell-tissue interactions

CECAD Uhlirova Lab of Development and Cancer

We are one of the largest and oldest universities in Europe and one of the most important employers in our region.

make us attractive for students and researchers from around the world. We offer a wide range of career opportunities
in science, technology, and administration.

Faculty of Mathematics and Natural Sciences