Molecular Biologist/computational Biologist - Oldenburg, Deutschland - Carl von Ossietzky Universität Oldenburg

Beschreibung

The School VI of Medicine and Health Sciences includes the areas of Human Medicine, Medical Physics and Acoustics, Neuroscience, Psychology and Health Services Research.

Together with the four regional hospitals the School VI forms the Oldenburg University Medical Center. We also cooperate closely with the University Medical Center at the University of Groningen.

In the division for Medical Genetics of the Department of Human Medicine there is a vacancy for a


Molecular biologist/Computational biologist (M/F/d) / (PhD)
(Salary according to TV-L E13, 75%)

to be filled
as soon as
possible for a limited period of 3 years (potential extension). There is the possibility of personal scientific qualification [doctorate thesis].

The position will be hosted at the Institute of Medical Genetics, University of Oldenburg. Our group uses multi-omic approaches (genomic, transcriptomic, and epigenomic) to elucidate the molecular basis of congenital heart diseases (CHD).


Tasks include:

• Implement protocols for WGS, longread nanopore sequencing, and transcriptomics analysis of CHD patients.
• Establish bioinformatic pipelines for evaluating CHD patients' NGS, nanopore, and transcriptomic datasets.
• Perform variant prioritization and pathogenic variants identification from nanopore sequencing datasets using bioinformatic tools (for example, Guppy, EPI2ME).
• Establish experimental studies to evaluate the functional impact and describe the molecular mechanism of pathogenicity of identified variants.
• Preparation of research manuscripts and collaboration on scientific projects.
• Collaboration in teaching.

Required qualifications:

• Completed university studies in natural/computational sciences and/or relates (Master's Degree or equivalent).
• Biostatistical knowledge
• Strong communication skills in English (spoken and written)
• Teamoriented working style
• Previous experience with research in the field of CHD
• Experience with NGS, longread sequencing, genomics and genomics data analysis
• Wetlab experience with cell culture and functional evaluation of pathogenic genetic variants.
• Experience in preparing human pathology sections and stainings.

Preferred qualifications:

• Experience with NGS protocols and its downstream analysis
• Programming skills in R and Python

We offer:

• An interdisciplinary and collaborative environment that supports innovation and professional development of team members.
• Participation in the development of a young university team with creative freedom.
• The possibility of independent scientific project work.
• Collaboration with national and international teams and consortia.
• Payment in accordance with collective bargaining law (particular annual payment, public service pension scheme, assetrelated benefits) incl. 30 days annual leave
• Support and guidance during your onboarding phase
• A familyfriendly environment with flexible working hours (flexitime) and the possibility of prorata mobile work
• Benefits from the university's health promotion program

The University of Oldenburg aims to increase the proportion of women in the academic field. Therefore, women are strongly encouraged to apply. According to - 21 para. 3 NHG, female applicants should be given preferential consideration if their qualifications are equivalent.

Applicants with disabilities are given preference in the event of equal suitability.