In Silico Biology Scientist - Aachen, Deutschland - Grünenthal

Grünenthal

Geprüftes Unternehmen

Aachen, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

Country:

Germany
City:Aachen
Department:Research & Development
Job ID:43042- If you're passionate about changing lives for the better, this is the opportunity you've been waiting for.

In
-
Research & Development, we're continuously exploring innovative new treatment options to make a stronger, more positive impact on the lives of the patients we serve. You'll work with talented colleagues in a state-of-the-art Research & Development environment, developing innovative medicines that change the live of patients for the better and help us make progress towards our vision of a world free of pain. Join us today, and discover the difference you can make.
What the job looks like
Each day you'll enjoy a variety of challenges, such as:

Drive implementation of innovative computational methods and techniques for identifying novel pain pathway and target insights, translational biomarkers and patient stratification
Deliver data analytic platform to integrate single cell multiomicsfunctional genomics, patientlevel data leveraging AI/ML/DL techniques to identify novel drug targets in pain
Correlate genomic data (human genetics and functional genomic datasets) against clinical/patient phenotypic data to discover novel pain disease insights and biomarkers for response/resistance to therapy
Present and communicate key findings to relevant stakeholders to enable datadriven decision making across research pipeline.
Ensure findings from computational biology work are appropriately incorporated into the asset strategies and more specifically into clinical translation and early clinical development plan (CDP) for the asset
Initiate, design and establish external collaborations anchored in in silico biologys to inform target selection, efficacy/safety assessment and derisking of assets
Be responsible to integrate other efforts within our research group focused on human cellbased models and systems biology

What you'll bring to the table
To make the most of this role and truly thrive, you should have:

PhD in computational biology/bioinformatics/systems biology with either postdoctoral or relevant industry experience
Demonstrated recent ability to design and lead human omics studies (with a variety of study designs) delivering novel and actionable findings with measurable impact on R&D pipeline (e.g. generated novel targets/projects that advanced to clinical stage, identification of biomarkers used in pre/clinical settings)
Proven expertise in working with multiple omics data sets at bulk and single cell resolution
Expert in programming with R and/or Python
Broad experience in training and evaluating machine learning models leveraging frameworks such as Tensorflow, Keras, Pytorch
Prior experience with high performance computing environments and cloud technology
In depth knowledge of various external databases employed in omics & systems biology research to be able to explore their applicability for Grunenthal portfolio
Fluent business English language skills in speaking and writing, German language skills beneficial
Broad international & intercultural working experience

What are some of the local benefits

Hybrid working model
Bilingual daycare centre "Karlinis" and holiday activities for employees' children
30 holidays, plus 68 bridging days and possibility to convert salary into up to 5 additional holidays

- (E-) Bike leasing and e-charging stations

Chanchal Kumar, the Hiring Manager