Postdoctoral Scientist - Mainz, Deutschland - Deutsches Krebsforschungszentrum

Deutsches Krebsforschungszentrum

Geprüftes Unternehmen

Mainz, Deutschland

vor 2 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

Position:
Postdoctoral Scientist - High-throughput Immunopeptidomics Platform**
Department: HI-TRON Mainz

Code number:

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

The Helmholtz Institute HI-TRON is a collaboration of the German Cancer Research Center (DKFZ) with the Research Institute for Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz (TRON gGmbH), the University Medical Center Mainz and the Johannes Gutenberg University Mainz.

The goal of the partnership is to develop effective immunotherapies and to identify novel biomarkers for assessing the effectiveness of treatment.

For the High-throughput Immunopeptidomics Platform at HI-TRON Mainz, we are seeking a postdoctoral scientist to join the team as soon as possible.

The platform aims to identify cancer-specific immunopeptides (MHC-ligands), antigens that can trigger the immune response and potential targets for immunotherapy.

To achieve this, we develop and implement LC-MS-based workflows to scrutinize the immunopeptidome in clinical, preclinical, and in vitro studies.

Headed by Dr. David Gomez-Zepeda, the platform was founded in June 2023 to provide scientists with cutting-edge LC-MS immunopeptidomics infrastructure and expertise. We are associated with the lab of Prof. Dr. Stefan Tenzer, forming a team of international and multi-disciplinary scientists in an innovation-driven environment.

Job description:

The project objective is to develop high-throughput workflows for sample preparation, LC-MS acquisition, and/or data analysis of immunopeptidomics experiments. To facilitate clinical studies, the goal is to achieve the analysis of hundreds of samples per week.

The scientist will contribute to collaboration projects from the study design to data analysis and interpretation, aiming to identify antigens in diverse types of cancer in cell culture, tumor, and plasma samples.

The specific goals will be adapted to the profile and interests of the selected applicant.

Main tasks:

Planning and performing experiments and analyzing, interpreting, and reporting the results
Communicating with collaboration partners and assisting in the coordination of students and technical staff
Writing scientific publications and presenting at national and/or international conferences
Optional: operating and maintaining LC-MS instruments (Evosep-One coupled to timsTOF Ultra), and/or the sample preparation robot (Opentrons)

Requirements:

D. with up to 4 years of postgraduate professional experience or M.Sc. with more than two years of experience in biochemistry, biotechnology, analytical chemistry, bioinformatics, computational biology, or related fields

Keen interest in bioanalytical chemistry, mass spectrometry, biochemistry, immunology, and/or oncology
Previous experience with MSbased omics and related data analysis is an advantage, but not required
Strong communication skills in English are required, knowledge of German is advantageous, but not required
Creativity and strong analytical thinking
Enthusiastic and motivated team player

We offer:

Interesting, versatile workplace
Excellent framework conditions: stateoftheart equipment and opportunity for international networking at the highest level
Remuneration according to TV-L incl. occupational pension plan for the public service and capitalforming payments
30 days of vacation per year
Flexible working hours
Possibility of mobile work and parttime work
Familyfriendly working environment, including parentchild room, counseling services, e.g. on Elder Care
Sustainable travel to work: subsidized Germany job ticket
Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents
Our Corporate Health Management Program offers a holistic approach to your wellbeing

Important notice:

Earliest possible start date:
as soon as possible

Duration:
The position is initially limited to 2 years with the possibility of prolongation.

The position can in principle be part-time.

Application deadline:

Contact:

Dr. Julia Neuhaus
Phone

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented.

Qualified female applicants are therefore particularly encouraged to apply.