Postdoctoral Position in T Cell Tumor Immunology - Freiburg, Deutschland - Universität Freiburg

Universität Freiburg

Geprüftes Unternehmen

Freiburg, Deutschland

vor 2 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

The Lillemeier laboratory for Molecular Immunology is searching for a Postdoctoral position in T cell tumor immunology

Bewerbungsfrist:
Veröffentlicht:
Startdate: At the earliest possible date.
Fulltime position
Kennziffer:

Beschreibung:

The Lillemeier Lab is seeking a highly motivated and innovative postdoctoral fellow to investigate novel strategies for cancer immunotherapies.

Our group is interested in how T cell activity and function is regulated during immune responses. Ongoing research focuses on the activating T cell receptor (TCR) and inhibitory PD-1 receptor pathways. We are identifying novel molecular mechanisms through multidisciplinary approaches that combine cellular immunology with microscopy, biophysics and biochemistry.

Specifically, we have discovered that post-translational modifications control the activities of ZAP70 kinase and SHP2 phosphatase through conformational changes and receptor interaction dynamics.

The goal of this postdoctoral position is to characterize these novel mechanisms in mouse tumor models _in vivo_ to determine if they are suitable targets for future immunotherapies.

Requirements:

PhD in immunology, virology, cell biology or related field.
Publication(s) in peerreviewed journals.
Expertise in mouse work, ideally with tumor models. A license to work with animals in the EU (e.g. FELASA certificate) is preferred.
Expertise in multiparameter flow cytometry. If required, additional training for spectral flow cytometry will be provided.
Experience with _in vitro _immunological assays and tissue culture.
Familiarity with RNA sequencing and/or TCR repertoire analysis will be useful, but is not required.

To Apply:

Please include a brief letter of motivation, a description of current research accomplishments and future research interests/goals (not more than one or two pages), CV with publication list and 3+ contact details for referees.

This full-time postdoctoral position is available immediately (or as soon as possible) for an initial term until 31st of December 2025 with possibility of extension.

The salary will be determined in accordance with E13 TV-L.

Bewerbung:

Universität Freiburg
Institut für Biologie III/HMH
Prof. Björn Lillemeier
Habsburgerstr. 49
79104 Freiburg