Lnp Formulation Director - Darmstadt, Deutschland - Merck

Merck

Geprüftes Unternehmen

Darmstadt, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics.

Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

Targeted mRNA delivery has the potential to change patient lives by enabling life changing therapies.

An M-Ventures funded biotech start-up is poised to seize the opportunity at the intersection between the Healthcare and Life Science Divisions of our company.

Our mandate is to think big and reach across disciplines to leverage the full capabilities of the organization.

With the agility of a startup and the resources of a leading multinational, the targeted mRNA delivery team is transforming the way researchers develop mRNA therapies.

For more than 350 years and across the world we have passionately pursued our curiosity to find novel and vibrant ways of enhancing the lives of others.

Your role:

As a founding member of the stealth startup leadership team, you will drive a multifunctional team designing a cutting-edge lipide nanoparticle (LNP) design platform which will enable the therapeutic delivery of mRNA.

Reporting to the startup "CEO", you will have shared responsibility for the success and growth of the venture.

Responsibilities include:
Build up a team to execute the mRNA vision with capabilities in:

LNP formulation
LNP screening, including biodistribution
High throughput synthesis and analytical workflows
Digital and data science capabilities including, but not limited to modelling, machine learning and predictive methods

Key elements of roadmap include:

Employ digitally enabled design of experiments, in collaboration with Digital Director
Enable generation and structure of large data sets to enable building of predictive formulation model
Streamline experimental workflow to maximize data generation and minimize time/cost
Design and synthesize novel lipids to enable targeting

Organization:
help build a multifaceted team capable of both lipid design innovation and high throughput experimentation

Laboratory:
equip and organize a state-of-the-art synthesis and screening laboratory

Ecosystem:
collaborate / best practice sharing with mRNA/LNP experts

Who you are:

PhD in life science, pharmacy, or engineering or a related field
A minimum of 7 years of proven experience in LNP design and synthesis
Familiar with Pharma or Biopharmaceutical industry, especially drug discovery
Demonstrated experience in high throughput screening platforms
Experience with _in vivo_ high throughput screening is advantageous
Knowledge on setting up and managing a data lake enabling digital approaches is beneficial
Experience managing multifunctional teams across geographies
Ability to manage multiple stakeholders and complex projects simultaneously
Highly organized, detailoriented, creative, resultsdriven problem solver with demonstrated flexibility and collaborative working style
Ability to work effectively, in a global, matrixed organization across multiple time zones
Proficient in English
Willingness to travel <20% (national and global travel)

What we offer:
We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences.

We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology.

We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress
Equal Employment Opportunities
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No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.

This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment.

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