Phd (M/F/d) - Heidelberg, Deutschland - Universitätsklinikum Heidelberg

Universitätsklinikum Heidelberg

Geprüftes Unternehmen

Heidelberg, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

as soon as possible searched for
Department of Internal Medicin III to work at
the Lab of Dr. Timon Seeger.

Recently, we were able to show a significant role for the ATF4pathway in relation to serine nenovo biosynthesis in the regulation of contractility in dilative cardiomyopathy. Here, a novel therapeutic approach has been identified which will be further explored in regard to its translational potential in heart failure.

Job-ID:

V

Klinik für Kardiologie, Angiologie und Pneumologie

Location:

Heidelberg

Start date:

as of now

Job Category:

Science and teaching

Working hours:

Part time (65 %)

Published:

Limitation:

Temporary (3 Jahre)

Contract:

TV-L

Tasks and responsibilities:

***- Exploration of the ATF4/serine de-novo synthesis pathway in dilative cardiomyopathy employing iPSC technology (with genome editing) as well as gene therapy approaches.

Expansion and differentiation of human iPSC to cardiac cell types (i.e. cardiomyocytes, fibroblasts)
Functional, cellular and molecular characterization of the derived cardiac cell types
Collaboration with research groups in regards to animal experiments
Summarazing of results for scientific presentations and publication

Prerequisites:

***- Experience in molecular methodologies (qPCR, western blot, cloning etc.) and cellular evaluation (immunostaining, transfection, etc.)

Experience in cell culture techniques (ideally using human induced pluripotent stem cells)
Knowledge of cell metabolism regulation and evaluation (eg. Seahorse, plate reader assays)

We offer:

***- Collectively agreed remuneration, attractive company pension scheme (VBL)

30 days vacation
Sustainable travel: job ticket
Familyfriendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
Wide range of health, prevention and sports offers

Contact & Application:

***
Interested?
Applications will be accepted unti August 15th.

Klinik für Kardiologie, Angiologie und Pneumologie

Dr. Timon Seeger
Im Neuenheimer Feld 410

HeidelbergWe stand for equal opportunities. Severely disabled persons are given priority in the case of equal suitability.

The University Hospital aims to generally increase the proportion of women in all areas and positions in which women are underrepresented.

Qualified women are therefore particularly encouraged to apply. Full-time positions are generally divisible, unless there are official or legal reasons to the contrary.