Bioinformatician / Computational Biologist - Heidelberg, Deutschland - Deutsches Krebsforschungszentrum

Deutsches Krebsforschungszentrum

Geprüftes Unternehmen

Heidelberg, Deutschland

vor 3 Wochen

Geschrieben von:

Lena Wagner

beBee Recruiter

Beschreibung

Position:
Bioinformatician / Computational Biologist**
Department: German Human Genome-Phenome Archive

Code number:

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Together with global partners and coordinated by "Hopp Children's Cancer Center Heidelberg" (KiTZ), the DKFZ has recently launched the "ITCC (Innovative Therapy for Children with Cancer) International Data Integration Platform" program.

The program strives to develop a cross-border IT platform for the use of, and access to, existing genomic and clinical data in pediatric oncology.

Together with other local and international initiatives connected to the project, we aim to contribute significantly to the development of new cancer therapies for children in Europe and beyond.

In the context of this initiative we plan to implement a state-of-the-art bioinformatics data infrastructure for the secure analysis of Omics Data in a federated mode with other international partners.

This is closely linked to other connected activities at the DKFZ, most notably the German Human Genome-Phenome Archive (GHGA), the genomDE program and the European "Genomics Data Infrastructure (GDI)" project.

The position will be situated between the GHGA main office at DKFZ, the research group of Prof. Oliver Stegle (Division of Computational Genomics and Systems Genetics) and the bioinformatics teams at the KiTZ.

Job description:

Development of a standardized workflow framework using cloud environments
Workflow development and maintenance for NGS data processing and analysis for canonical tasks
Improvement of bioinformatics workflows with respect to performance and stability
Testing / benchmarking workflows with cloud deployments
Development of cloud images for (human) bioinformatics
Develop, test, and maintain genomics web services in accordance with GA4GH standards
Integrate GDI and GHGA web services
Collaboration with local and international developers

We offer the opportunity to help shape one of the most important emerging scientific data infrastructures for the storage and exchange of omics data in Germany.

Your possibilities:

Get exposed to a plethora of fields ranging from AIguided clinical decision making to modern web development technologies
Work with an interdisciplinary team of experts bringing stateoftheart biomedical research closer to clinics and patients
Take part in international organizations such as the Global Alliance for Genomics and Health (GA4GH), the European Genome-Phenome Archive (EGA) and ELIXIR shaping the future of genomics across borders
Widen your expertise with extensive possibilities of training programs, seminars and conferences

Requirements:

PhD in computer science, mathematics, physics, bioinformatics, computational biology or similar background with focus on bioinformatics or data science;
Alternatively a MSc or equivalent qualification with complementary years of relevant experience
Handson experience with workflow development and genomics data analysis using open source software and algorithms, using workflow languages (WDL, CWL, Nextflow)
Familiarity with GA4GH standards, such as Beacon, Crypt4GH, DRS, TES, and WES is an advantage
Proficiency with Pythonbased web frameworks (e.g. FastAPI, Flask, Django)
Familiarity with database and search engine setups (e.g. MongoDB, ElasticSearch)
Familiarity with testdriven software development
Experience or interest in microservices design patterns and domaindriven design
Over 2 years of experience with software containerization tools like Docker, Singularity
Proficiency with UNIXbased systems and relevant programming languages such as Python or R is a prerequisite
Expertise in software development and cloud computing is beneficial

If you have any questions, please do not hesitate to contact Dr. Jan Eufinger and Luiz Gadelha

We offer:

Excellent framework conditions: stateoftheart equipment and opportunities for international networking at the highest level
Remuneration according to TV-L incl. occupational pension plan and capitalforming payments
30 days of vacation per year
Flexible working hours
Possibility of mobile work and parttime work
Familyfriendly working environment, e.g. parentchild room, advisory services caring for elderly relatives
Sustainable travel to work: subsidized Germany job ticket
Unleash your full potential: targeted offers for your personal development to further develop your talents
Our Corporate Health Management Program offers a holistic approach to your wellbeing

Important notice:

Earliest Possible Start Date:

Duration:
The positions are initially limited to 2 years with the possibility of prolongation.

The position can in pri