Academic Research Assistant - Saarbrucken, Deutschland - Universität des Saarlandes
Beschreibung
Saarland University is a campus university that is internationally recognized for its strong research programmes.Fostering young academic talent and creating ideal conditions for teaching and research are a core part of the
university's mission. As part of the University of the Greater Region, Saarland University enables students and staff to
share and exchange knowledge and ideas between disciplines, between universities and across borders. With over
17,000 national and international students, studying more than a hundred different academic disciplines, Saarland
University is a diverse and dynamic learning environment. [Saarland University is officially recognized as one of
Germany's family-friendly higher-education institutions and with a combined workforce of more than 4,000 it is one
of the largest employers in the region.]
commencing at the earliest opportunity.
Academic research assistant (PhD position) (M/F/x)
Reference number W2483, salary in accordance with the German TV-L salary scale1, pay grade: E13 TV- L, duration
of employment:
initially 3 years, volume of employment: 50 % of standard working time.
Workplace/Department:
Regulation of protein translocation across the endoplasmic reticulum (ER) membrane: Proteins are transported
through the ER membrane for biosynthetic protein import of secretory and transmembrane proteins by the Sec61
channel. So far, little is known about regulation of Sec61 channel activity. We are currently investigating the role of
phosphorylation on transport through the Sec61 channel, and identifying proteins whose secretion is regulated. We
have recently shown that the phosphorylated channel subunit is essential for virulence of a major human fungal
pathogen. We employ a mixture of protein biochemistry, yeast genetics, and cell-free assays to address these questions.
to a high standard. The lab language is English, but acquisition of at least rudimentary German is desirable. The thesis
a year, and in co-supervising BSc and MSc students alongside their thesis work. PhD students are expected to finish
within 3-4 years with at least one first-author publication.
1 TV-L = collective agreement on remuneration of public sector employees in the German _Länder _
The pay grade assigned to an employee depends on their professional qualifications and the number of years of service. Each pay grade is
further subdivided into levels. Entry-level employees with no previous experience will initially be assigned a level 1 rating. After one year at
level 1 of the E10 pay grade, an employee will move up to level 2. After a further two years, the employee will move to level 3, etc.
Barbieri G, Simon J, Barbarit A, Lupusella C, Pereira F, Elia F, Meyer H, Schuldiner M, Hanes SD, Nguyen D, Helms V, Römisch K ER translocation of
suboptimal targeting sequences depends on Sec61beta/Sbh1 and is fine-tuned by phosphorylation. J Biol Chem 299:102895.
Santiago Tirado F, Hurtaux T, Helms V, Geddes-McAlister J, Nguyen D, Helms V, Doering T, Römisch K The ER protein translocation channel
subunit Sbh1 controls virulence of Cryptococcus neoformans. mBio 14(1):e
Bhadra P, Yadhanapudi L, Römisch K, Helms V How does the presence/absence of Sec63 affect Sec61 conformations? PLoS Computational Biology
17(3):e
Elia F, Yadhanapudi L, Tretter T, Römisch K The N-terminus of Sec61p plays key roles in ER protein import and ERAD.
Job requirements and responsibilities:
yeast genetics, protein biochemistry, or cell-free assays would be helpful. PhD students are expected to finish
within 3-4 years with at least one first-author publication.
Your academic qualifications:
- Completed scientific university studies in Moleculary Biology, Biochemistry, or a similar field including a BSc and
- participate in teaching 2 practicals per year,
- participate in supervision of BSc and MSc students,
- Language skills: the lab language is English, but acquisition of rudimentary German would be desirable.
What we can offer you:
- A flexible work schedule allowing you to balance work and family, among other things the possibility of
- Secure and futureoriented employment with attractive conditions,
- A broad range of further education and professional development programmes (for example language courses),
- An occupational health management model with numerous attractive options, such as our university sports
- Supplementary pension scheme (RZVK),
- Discounted tickets on local public transport services ('Job-Ticket Plus' of the saarVV),
If you have any
questions, please contact us for assistance
Your contact:
Dr. Karin Römisch
Professor of Microbiology
Pay grade classification is based on the particular details of the posit
Mehr Jobs von Universität des Saarlandes
-
W3 Professorship in Structural Biology
Saarbrucken, Deutschland - vor 2 Wochen
-
Wissenschaftliche Mitarbeiterin/ Wissenschaftlicher
Saarbrucken, Deutschland - vor 2 Wochen
-
Technische r Assistent in in Der Forschung
Saarbrucken, Deutschland - vor 1 Woche
-
W3-professur Für Theoretische Philosophie
Saarbrucken, Deutschland - vor 1 Woche
-
Wissenschaftliche Mitarbeiterin/ Wissenschaftlicher
Saarbrucken, Deutschland - vor 1 Woche
-
Wissenschaftliche Mitarbeiterin/ Wissenschaftlicher
Saarbrucken, Deutschland - vor 2 Wochen