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    PhD Student Position in Computational Biology – Somatic Evolution of Cancer Development - Heidelberg, Deutschland - Deutsches Krebsforschungszentrum (DKFZ)

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    Beschreibung

    The German Cancer Re­search Center is the largest bio­medi­cal re­search insti­tu­tion in Germany. With more than 3, employees, we operate an exten­sive scien­tific program in the field of cancer research.

    The Junior Research Groups "Somatic Evolution and Early Detection" and "Experimental Hepatology, Inflammation and Cancer" are jointly offering a

    PhD Student Position in Computational Biology – Somatic Evolution of Cancer Development

    (Ref-No. -)

    The Junior Research Groups of Dr. Angela Goncalves (Somatic Evolution and Early Detection) and Dr. Dr. Michael Dill (Experimental Hepatology, Inflammation and Cancer) are looking for a highly motivated and skilled PhD student to join a collaborative project with the goal of investigating the somatic evolution of cancer development in primary sclerosing cholangitis (PSC) by integrating large scale genomics analyses with single-cell transcriptomics with access to one of the largest organoid biobank from PSC patients.

    Our research groups are committed to advancing the understanding of cancer development in chronically inflamed organs, such as liver. Our work involves cutting-edge organoid technology, genomics, single-cell transcription analysis, and computational modelling to unravel the complexities of somatic evolution during carcinogenesis.

    Description:

    You will be jointly affiliated with the laboratory of Dr. Goncalves and Dr. Dill to improve our understanding of somatic evolution in early carcinogenesis and will be working with an interdisciplinary team consisting of physician-scientists, biologists and bioinformaticians.

    Your activities will comprise:

    • Designing and analyzing novel single-cell transcription experiments using cutting-edge bioinformatics tools
    • Analyzing genomic data and computational modelling of somatic mutations

    Your profile:

    • Master's degree or equivalent qualification in computer science, mathematics or physics, or a degree in biological sciences with demonstrated experience in computational biology
    • Programming skills in R or Python
    • Motivation and dedication to lead a scientific project
    • Excellent communication and collaboration skills, including a good command of written and oral English
    • Ability to work independently and be a supportive and responsible team member
    • Experience with next-generation sequencing techniques is a plus

    Applications should consist of a single PDF file including a curriculum vitae, a cover letter stating research and career interests, transcripts of records of both bachelor and master studies, letter of recommendation and contact details of two referees.

    We offer:

    • Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
    • Access to international research networks
    • Doctoral salary with the usual social benefits
    • 30 days of vacation per year
    • Flexible working hours
    • Possibility of part-time work
    • Family-friendly working environment, e.g. parent-child room, advisory services
    • Sustainable travel to work: subsidized Germany job ticket
    • Unleash your full potential: targeted training and mentoring through the DKFZ International PhD Program and DKFZ Career Service
    • Our Corporate Health Management Program offers a holistic range of services for your well-being

    The position is initially limited to 3 years.

    Important notice:

    The DKFZ is subject to the regulations of the Infection Protection Act (IfSG). As a consequence, only persons who present proof of immunity against measles may work at the DKFZ.

    For further information please contact
    Dr. Dr. Michael Dill, phone /42-.

    The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.

    Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.

    To apply for a position please use our online application portal (

    We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebs­forschungs­zentrum, Personal­abteilung, Im Neuen­heimer Feld , Heidelberg) and that we do not accept applications submitted via email. We apolo­gize for any inconvenience this may cause.



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